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Asymmetric Brook Rearrangement
Nicholas Lee, Prof. Choon‐Hong Tan and Dr. Dasheng Leow
Asian Journal of Organic Chemistry, 2019, 8, 25-31
Abstract: Although the Brook rearrangement has been discovered over fifty years ago, there remains significant opportunities for chemists to make new discoveries relating to this reaction. Majority of the examples in the literature report Brook rearrangements using racemic starting materials. In this Focus Review, we highlight asymmetric variants of Brook rearrangements, focusing on enantioselective and enantiospecific examples.
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