top of page
Search
  • TCHLab

Tandem conjugate addition–elimination reaction promoted by chiral pyrrolidinyl sulfonamide (CPS)

Junye Xu, Xiao Fu, Ruijuan Low, Yong-Peng Goh, Zhiyong Jiang and Choon-Hong Tan

Chem. Communi., 2008, 5526–5528. (Highlighted by Douglass F. Taber, Org. Chem. Highlights 2009, August 10).


Abstract: Chiral pyrrolidinyl sulfonamides have been found to promote the conjugate addition–elimination reaction between activated allylic bromides and 1,3-dicarbonyl compounds with high enantioselectivities and the highly functionalised products can be used to generate a variety of interesting enantiomerically pure compounds via simple transformations.


Paper download:


4 views0 comments
bottom of page