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Synthesis and characterization of circular structures of i-Motif tagged with Fluoresceins

  • TCHLab
  • Mar 30, 2009
  • 1 min read

Tianyan Zhou, Xinming Li, Magdeline Tao Tao Ng, Yifan Wang, Ngee Mien Quek, Ji Luo, Weixing Yuan, Choon-Hong Tan, Huaqiang Zeng and Tianhu Li

Bioconjugate Chemistry, 2009, 20, 644–647.


Abstract: Synthesis of a fluorescein-tagged circular structure of i-motif was accomplished during our investigations. The backbone circularity of this molecular probe and the presence of the fluorescent moiety within its structure were also confirmed through exonuclease hydrolysis and fluorescence spectroscopy.


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