Recent Advances in Chiral Guanidine-Catalyzed Enantioselective Reactions

Abstract

Chiral guanidines have been widely used as Brønsted base catalysts and phase transfer catalysts in enantioselective reactions. Due to their amendable structure and powerful catalytic ability, they have attracted much interest. Several new catalysts containing a guanidinium moiety have been reported over the past decade and many promising outcomes have been achieved. This article illustrates the progress of chiral guanidine catalysis in asymmetric synthesis from 2009 to 2018. It is an update of a review of the same title published in 2009.

Full text available at: https://onlinelibrary.wiley.com/doi/pdf/10.1002/asia.201901183