Chiral bicyclic guanidine as a versatile Brønsted base catalyst

- for the Enantioselective Michael Reactions of Dithiomalonates and β‐Keto Thioesters

Weiping Ye, Zhiyong Jiang, Yujun Zhao, Serena Li Min Goh, Dasheng Leow, Ying‐Teck Soh and Choon‐Hong Tan

Adv. Synth. and Catal., 2007, 349, 2454–2458.

Abstract: A chiral bicyclic guanidine was developed as a versatile Brønsted base catalyst for the enantioselective Michael reactions of dithiomalonates and β‐keto thioesters using a range of acceptors including maleimides, cyclic enones, furanone and acyclic 1,4‐dicarbonylbutenes.

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